Scientists find link between AstraZeneca vaccine and deadly blood clots – .

Scientists find link between AstraZeneca vaccine and deadly blood clots – .

According to researchers, the biological process that leads to the formation of fatal blood clots in some people after the discovery of the AstraZeneca jab.

Scientists at Cardiff University have found that a protein in the blood likes to bind to part of the vaccine, which can lead to dangerous clotting.

Oddly enough, the reaction is not caused by the coronavirus particles in the vaccine, but by the system used to deliver it inside the body.

The AstraZeneca vaccine encapsulates the genetic material of the coronavirus in a weakened version of the common cold virus, known as the adenovirus, which infects chimpanzees.

The new study shows that the adenovirus attracts a protein called “platelet factor four” like a magnet.

This new protein-virus hybrid disrupts the immune system, which creates new antibodies, which in turn adhere to proteins, causing dangerous blood clots to form.

The process only happens infrequently, which is why few people are affected by the disease.

Clots have been linked to 73 deaths out of 50 million doses of AstraZeneca in the UK.

Cardiff University has received government funding to find the cause of the clotting. Researchers soon realized that people with clots had extra antibodies that attacked “platelet factor four”.

“The trigger and the smoking gun”

Professor Alan Parker, one of the researchers at Cardiff University, told BBC News: ‘Adenovirus has an extremely negative surface, and platelet factor four is extremely positive and the two things fit together quite well. . “

He added: “We were able to prove the link between the main smoking guns of adenoviruses and platelet factor four.

“What we have is the trigger, but there are a lot of steps that need to happen next. “

The AstraZeneca vaccine is said to have saved more than a million lives worldwide and prevented 50 million cases of Covid-19.

“While the research is not definitive, it offers some interesting information and AstraZeneca is exploring ways to take advantage of these findings as part of our efforts to remove this extremely rare side effect,” said a spokesperson for the manufacturer of vaccines.

Researchers have so far only shown the binding effect in lab experiments, but say it “provides a mechanism” by which clotting could occur.

They hope their findings can be used to design vaccines that don’t trigger this reaction, and therefore be safer.

At this time, the AstraZeneca vaccine is not offered to people under the age of 40 because the risks of blood clotting are thought to outweigh the benefits of the vaccine.

The research was published in the journal Science Advances.


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