Moderna’s COVID-19 vaccine proves to outlast Pfizer rival, provincial health official says – .

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Moderna’s COVID-19 vaccine proves to outlast Pfizer rival, provincial health official says – .


“As I have said several times, we do not yet have absolute correlative protection (100% protection), but Moderna appears to give higher levels of antibodies which stay longer,” says Dr Bonnie Henry. .

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The COVID-19 vaccine produced by Moderna is proving to be more durable than rival Pfizer and better suited as a booster vaccine for some severely immunocompromised people, according to British Columbia provincial health officer Dr Bonnie Henry.

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Both vaccines are approved for use in Canada and widely used in British Columbia

At a press conference last week, Henry said his office was getting more and more information about which vaccines worked as well or better than others – based mostly on studies of COVID antibodies. -19 remaining in people’s blood after vaccination.

This antibody response is crucial for the functioning of vaccines, because it is this response that fights the disease.

“As I’ve said a number of times, we don’t have absolute correlative protection (100% protection) yet, but Moderna appears to give higher levels of antibodies that stick around for longer,” Henry said.

This was probably due to the fact that the Moderna mRNA vaccine contains a higher amount of antigen (the substance that creates an immune response) than the Pfizer vaccine.

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“It’s not surprising if you think about it. (Moderna has a) higher amount of antigen – the mRNA it contains – compared to Pfizer, and it seems to give a stronger response.

So far, 83% of British Columbians aged 12 and over are fully immunized – and the provincial government has launched its booster program, giving a third dose of the vaccine to people in long-term care facilities and to those who are moderately or severely immunocompromised. .

Henry said the booster doses will be either Moderna or Pfizer, but Moderna has proven to be the most effective option in some cases.

“The studies that were done with a third dose using Moderna yielded a higher proportion of people who developed a strong immune response,” Henry said.

“So we said preferably that people should use Moderna if you are someone who has had a solid organ transplant. This gives the best possible chance of strengthening this immune system and making it progress. “

However, it is not clear whether Moderna has an advantage over Pfizer for people in long-term care.

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The province began providing booster shots to seniors in long-term care facilities in early October and is now preparing to give third doses to 100,000 more people, including those who are severely and moderately immunosuppressed . People on dialysis or with severe kidney or kidney disease will also be told when they can expect their third injection.

Henry said information on booster shots for other people, including First Nations, over the age of 60 and healthcare workers who were vaccinated early, should be provided by the end of the month. month.

Henry said there was more data available showing that mixing and pairing vaccines gives the body’s immune system several different ways to respond and this may result in a stronger and longer lasting response.

AstraZeneca and Johnson & Johnson vaccines are also approved by Health Canada, but are not used in British Columbia at this time.

– with files from the Canadian Press

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