Quarterbacks coach Cam Turner and defensive tackle Zach Allen will also miss the game due to positive tests.
Defensive coordinator Vance Joseph and assistant head coach / special teams coordinator Jeff Rodgers will split head coaching responsibilities on Sunday.
Kingsbury was in training on Friday. He also met the media inside in the morning and was unmasked. The media, who had to be vaccinated to attend, were all masked.
The team had not been informed Friday night who will call the games instead of Kingsbury.
The Cardinals are 100% vaccinated, Kingsbury had said, but the team faced issues related to the virus this week.
This placed outside linebacker Chandler Jones on the reserve / COVID-19 roster, and he is yet to come off, casting doubt on his status for Sunday’s game.
Discussing Jones’ positive test and how COVID is affecting the Cardinals in 2021, Kingsbury then said, “This is how it goes. We have been fully vaccinated now for some time. “
NFC West frontman Arizona is the only undefeated team in the NFL at 5-0.
Joseph has a background as a head coach, having led the Denver Broncos in 2017 and 2018.
Kingsbury, meanwhile, is not the first head coach to miss a game due to COVID.
Last season, Browns coach Kevin Stefanski missed a wildcard playoff game with a positive test. Darrell Bevell also missed a game last season as the interim coach of the Detroit Lions because he was considered close contact via COVID protocols. Tennessee Titans coach Mike Vrabel tested positive for COVID-19 at training camp this year, and former Philadelphia Eagles coach Doug Pederson tested positive at training camp on last year.