Latest government figures compare with 36,100 infections and 49 deaths reported Monday.
This time last week, 26,628 cases and 185 deaths were reported.
Since the start of the pandemic, 135,455 people have died in the UK within 28 days of a positive result coronavirus test.
See the latest COVID updates in the UK and around the world
Today’s figure is only the fourth time the number of daily deaths has exceeded 200 since March 9 of this year.
Another 24,684 people received their first dose of a COVID vaccine on Monday, bringing the total to 48,617,703 (89.4% of those over 16 in the UK).
Another 46,451 people received their second injection, which means that 44,512,572 are now fully vaccinated (81.9%).
It comes as the Prime Minister has said that canceling Christmas was “not the plan at all”.
Faced with the prospect of another COVID spike and a turkey shortage, Boris Johnson said the government “doesn’t expect something like last Christmas.”
He admitted there could be issues with supply chains affecting Christmas dinners, but at least he is keen on families being able to spend time together.
He highlighted the recall program – which the government hopes will keep cases under control – and plan B of measures, such as the reintroduction of face masks.
Meanwhile, COVID has now killed about as many Americans as the 1918-19 Spanish flu pandemic – about 675,000, according to Johns Hopkins University.
In the United States, deaths still amount to more than 1,900 per day. Modeling predicts that about 100,000 more Americans will die from the coronavirus by January 1.
In other news, Johnson told Brazilian President Jair Bolsonaro for “getting the AstraZeneca vaccine” in a clumsy exchange with the unvaccinated South American leader.
At a meeting, he told the executive that AstraZeneca is a “great vaccine”.
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