DeChambeau was due to represent his country at the event starting Thursday at Kasumigaseki Country Club, but received news of his positive test before leaving for Japan.
The 2020 US Open champion is the latest athlete to see his Olympic plans ruined by coronavirus. DeChambeau will be replaced by Patrick Reed, who will line up alongside Justin Thomas, Collin Morikawa and Xander Sc Chaudele.
“I am so excited to have the opportunity to represent our country and be part of Team USA in Tokyo,” said Reed. “I only wish Bryson the best, and I know how disappointed he is that he can’t compete, and I’ll do my best to play my best and represent our country. “
“I am deeply disappointed that I will not be able to compete in the Olympics for the American team,” said DeChambeau. “Representing my country means the world to me and it has been a huge honor to be part of this team. I wish Team USA good luck next week in Tokyo. I will now focus on my health and look forward to returning to competition once I get permission. “
DeChambeau is one of golf’s most controversial figures, earning the nickname “The Mad Scientist” due to his unorthodox approach to the game and his involvement in a public feud with Brooks Koepka.
Controversy also followed Reed throughout his career, but he once thrived in team golf at the Ryder Cup where he was the so-called “Captain America” of the American side.
Golf returned to the Summer Games after a 112-year absence at Rio 2016 when Justin Rose won gold for Team GB. Paul Casey and Tommy Fleetwood will represent the men of the GB team this year, with Jodi Ewart Shadoff and Mel Reid in the women.