Novavax Covid shot very effective variants compared to trials – –

Novavax Covid shot very effective variants compared to trials – –

Novavax Inc.’s Covid-19 vaccine candidate has shown high efficacy against the coronavirus in a large trial that signals that a new option is near for a global community still desperate to protect itself against the virus and its variants.
The shot was 90% effective in preventing symptomatic Covid and 100% effective in preventing moderate and severe symptoms, the US biotech company said said Monday in a statement. It was also 93% effective against the variants of concern, according to the results of a secondary analysis that mainly included cases of the predominant alpha variant in the United States.

The company plans to seek regulatory clearance globally, with most of the first available doses going to low- and middle-income countries, Stanley Erck, CEO of Novavax, said on a conference call. The study results, which were at least as good as many analysts expected, suggest that Novavax’s protein-based technology may be a rival to messenger RNA vaccines over time, especially if injected. reminders are needed.

The data “clearly positions Novavax as a viable alternative to mRNA vaccines,” Kelechi Chikere, analyst at Jefferies, wrote in a note to clients. Over time, Novavax’s vaccine could become a “universal booster” because of its high efficacy and low rate of side effects, Chikere said.

Novavax shares rose less than 1% to $ 210.56 at 10:36 a.m. in New York exchanges.

The vaccine uses recombinant protein technology, also used in the candidate developed by Sanofi and GlaxoSmithKline Plc. At over 90%, the overall vaccine efficacy is similar to the rates reported for messenger RNA injections developed by Pfizer Inc. with BioNTech SE and by Moderna Inc., as well as the Russian Sputnik V vaccine, using virus vector technology.

The Phase 3 trial of Novavax included nearly 30,000 participants in the United States and Mexico. Side effects of the injection, given in two doses 21 days apart, included headache, muscle pain and fatigue.


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