All Morgan Stanley staff in the New York metro area are also now required to certify their coronavirus vaccination status by July 1.
Employees who are not fully vaccinated will have to continue working remotely, the company told workers on Tuesday.
The move, which will allow Morgan Stanley to lift mask and physical distancing requirements in its offices, follows similar actions by other financial giants.
Blackstone said last month that U.S. workers in investment divisions could return to their offices full-time on June 7 if they are fully vaccinated against the coronavirus.
Goldman Sachs sent employees a note earlier this month requiring them to disclose their immunization status.
Previously, Morgan Stanley had only required employees in certain areas of the company to be fully immunized to return to their offices.
The Financial Times, citing a memo, first reported on Tuesday that Morgan Stanley would require employees, customers and visitors to the New York area to attest to being fully vaccinated in order to enter office spaces. company work in New York and Westchester County.