Randy Arozarena landed a starting single in the eighth and climbed to third on wild terrain from Sam Coonrod (0-2). After Yandy Diaz was intentionally knocked out with one out, Meadows made it 4-3 with his hit against Jose Alvarado.
Tampa Bay took a two-point lead when Alvarado walked pinch hitter Mike Brosseau with the base charge.
Diego Castillo (1-3) ended a two-on-two jam in the eighth for the Rays, who have won three in a row after Kansas City ended their 11-game winning streak on Tuesday. JP Feyereisen worked the ninth to get his second save.
Philadelphia starter Zack Wheeler allowed three runs, four hits, two walks and struck out a career-high 14 in seven innings. The right-hander made six starts in May, going 2-0 with 57 strikeouts, five walks and 11 runs in 43 1/3 innings.
Phillies right fielder Roman Quinn left the game in the fifth inning with a left Achilles tendon injury. He tripped and fell in third on Ronald Torreyes’ brace, got up and soon after had to go home on his right leg. Quinn ruptured his right Achiiles tendon during offseason training in 2013.
Matt Joyce, who replaced Quinn, tied at 3 on a solo homerun in the seventh inning against Jeffrey Springs. He had been without a hit in his previous 28 at-bat appearances.
Tampa Bay struck 16 times and Philadelphia struck 15 times. The Rays have beaten the Major League most 565 times, and the Phillies have 528.
Wheeler gave Yandy Diaz and Meadows unusual back-to-back goals with two strikeouts in the sixth before Ji-Man Choi gave the Rays a 3-2 lead on a single.
Torreyes finished Ryan Yarbrough’s day with a fifth inning hit that tied him at 2.
Yarbrough, winless in his last 24 starts since Aug. 17, 2019, allowed two runs, three hits, two walks and struck out eight in 4 1/3 innings. The southpaw, who often follows an opener, is 25-5 as a reliever.
Meadows hit a two-run homer in the first. He scored four points in the Rays’ 7-2 win over Kansas City on Thursday night. He has 26 RBIs in his last 23 games.
Phillies wide receiver JT Realmuto was reinstated from the 10-day injured roster after being eliminated with a left hand contusion and was scored 0 for 3 with a kick and volley base.
Spokes: RHP Chris Archer feels that the tendonitis in his right forearm has disappeared and it is now time to build strength in his arm. There is no date for his return but Archer would be happy for him to perform in early July.
Phillies RHP Zach Eflin (2-4) will start Sunday’s two-game series final. LHP Josh Fleming (4-3) could start or follow a first game for Tampa Bay.