Animal Rebellion said it has around 50 people at the Hemel Hempstead, Basingstoke, Coventry and Heywood distribution sites in Greater Manchester to prevent trucks from leaving depots.
They use trucks and bamboo structures as blockages.
Animal Rebellion said they intend to stay at the sites for at least 24 hours, causing “significant disruption” to McDonald’s supply chain.
The group is asking McDonald’s to commit to going all-plant by 2025.
James Ozden, a spokesperson for the group, said the action aims to call on the animal agriculture industry for its role in the global climate crisis.
He said: “The meat and dairy industry is destroying our planet: causing huge amounts of deforestation of the rainforest, emitting immense amounts of greenhouse gases and killing billions. animals every year.
“The only sustainable and realistic way to feed ten billion people is through a plant-based food system. Organic, outdoor, and “sustainable” animal-based options just aren’t good enough.
A tweet from Animal Rebellion read: “Locked down for workers’ rights, animal justice and to end the climate emergency.
“We are taking action to let global businesses know they need to change. THIS IS HAPPENING NOW. Since 430 in the morning. “
McDonald’s has been contacted for comment.