Jota was unable to recover from the foot problem that forced him to retire in the 4-2 win at Manchester United on Thursday.
The Portuguese are replaced by Sadio Mane in the starting lineup for the meeting at The Hawthorns.
This is one of two changes made by Reds boss Jurgen Klopp to the side that triumphed at Old Trafford.
Gini Wijnaldum is rested on the bench with Curtis Jones taking the Dutchman’s place in midfield.
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The youngster is joined by Fabinho and Thiago Alcantara in the engine room.
The defense remains the same for the third game in a row, with Rhys Williams partnering with Nat Phillips at center-back.
Alisson Becker is in the goal, with Trent Alexander-Arnold and Andy Robertson full-backs.
Mane joins Mohamed Salah and Roberto Firmino up front, with Liverpool’s injury list highlighted by young quartet Leighton Clarkson, Ben Woodburn, Neco Williams and Billy Koumetio all on the bench.
With Jordan Henderson, James Milner and Virgil van Dijk out and Wijnaldum among the substitutes, Firmino is the skipper for the afternoon.
A win will take the Reds one point away from the top four and Champions League qualifying places.
LIVERPOOL (4-3-3): Alisson; Alexander-Arnold, Phillips, R Williams, Robertson; Fabinho, Thiago, Jones; Salah, Firmino, Mane.
Submarines: Adrian, Wijnaldum, Tsimikas, Shaqiri, Origi, Woodburn, Clarkson, N Williams, Koumetio.