Two women in their 30s and a man in their 40s suffered from blood clots, leading to ischemic stroke – the most common type, caused by a blood clot that blocks the arteries and stops blood flow to the brain.
A team from University College London (UCL) Hospitals NHS Foundation Trust and other organizations have highlighted the risks of suffering a stroke due to the vaccine are small and stroke is more common in people who get coronavirus.
Experts at UCL’s National Neurology and Neurosurgery Hospital have said the NHS must seek out patients with this type of stroke within a month of receiving the COVID-19[feminine[feminine coup.
Any patient who suffers from a stroke should be “urgently evaluated” for a very rare syndrome called vaccine-induced thrombosis and thrombocytopenia (VITT).
The disease needs to be diagnosed quickly and managed by a team with a range of expertise, who have quick access to a range of drugs, they said.
The first patient to have a stroke, a 35-year-old Asian woman, had intermittent headaches on the right side and around her eyes six days after taking the vaccine.
She woke up drowsy and with weakness in her face, arm and leg five days later.
Despite brain surgery and other treatments, the women died.
Another person, a 37-year-old white woman, suffered from headaches, confusion, weakness in her left arm and loss of vision on her left side – 12 days after being vaccinated.
She received a range of treatments and survived.
The third patient, a 43-year-old Asian man, was admitted to hospital three weeks after being vaccinated with difficulty speaking and understanding the language.
He has received a platelet and plasma transfusion and other treatment and remains stable.
There have been 309 cases of VITT from more than 30 million doses of the AstraZeneca vaccine administered, or about one per 100,000 doses, according to experts.
Great Britain restricted use of AstraZeneca vaccine in people under the age of 40 this month, for fear of causing blood clots, anyone under the age of 40 will be offered an alternative.
The vaccine rollout has now been extended to people aged 30 and 31, which will be offered the Pfizer or Moderna jab.
“Our study shows that the much more common ischemic stroke, due to arterial thrombosis blocking blood flow to part of the brain, may also be a presenting feature of vaccine-induced thrombosis,” said David Werring, professor. of clinical neurology at UCL.
“Doctors should be vigilant if patients exhibit typical symptoms of stroke due to a blocked artery at any time between days 4 and 28 after vaccination. “
Subscribe to the daily podcast on Apple Podcasts, Google Podcasts, Spotify, Spreaker
Professor Hugh Markus, Department of Clinical Neuroscience, University of Cambridge, said: “It is important to remember that these side effects are rare and much less common than cerebral venous thrombosis and ischemic stroke associated with COVID-19. the infection itself. “
Dr June Raine, Director General of the Medicines and Health Products Regulatory Agency, said: “No effective drug or vaccine is without risk.
“These specific types of low platelet count blood clots reported after the AstraZeneca COVID-19 vaccine remain extremely rare and unlikely to occur.
“Our view remains that the benefits of the vaccine outweigh the risks for most people. ”