Dean Smith gave Grealish 20 minutes on Thursday in the goalless draw at Everton, with the captain’s game minutes due to be increased again here against Crystal Palace.
The big news for Villa comes at the back as Tyrone Mings misses an injury for the first time since December 28 as he is replaced by Kortney Hause.
Right-back Ahmed Elmohamady replaces injured Matty Cash after the latter was hampered by a hamstring against Everton on Thursday.
John McGinn is Villa captain this afternoon, with the Scotsman with Douglas Luiz and Jacob Ramsey in midfield. Ross Barkley quit.
In front of Villa, Watkins returns to the lineup after his one-game ban. Keinan Davis gives way.
Here are your line-ups for the 12pm kick-off this afternoon:
VILLA: Martinez; Elmohamady, Konsa, Hause, Targett; Douglas Luiz, McGinn; Traoré, J. Ramsey, El Ghazi; Watkins
Submarines: Steer, Taylor, Wesley, Grealish, Nakamba, Barkley, Engels, Davis, Chukwuemeka.
PALAIS: Butland; Ward, Kouyate, Cahill, Mitchell; Eze, McCarthy, Townsend; Schlupp, Benteke, Zaha.
Submarines: Hennessy, Guaita, Tomkins, Dann, Ayew, Mateta, Kelly, Batshuayi, Riedewald.