France brought in Matthieu Jalibert for the injured Teddy Thomas for the potential Six Nations title-maker on Saturday against Ireland.
Fly-half Jalibert arrives after winger Teddy Thomas, who scored a try in the weekend’s win over Wales, was ruled out with a hamstring injury.
Ireland lead the standings by one point and take the title with a bonus points victory in Paris.
A four-point win would open the door for England, which ends up against Italy.
The points difference would come into play assuming England win maximum points in Rome while third-placed France are also in the title race.
Thomas will be “unavailable for an unknown period” with a hamstring problem, the FFR announced on Tuesday.
Jalibert withdrew from the team two weeks ago for an unspecified medical reason, but the media claimed he tested positive for the coronavirus.
France could also be unlatched Bernard Le Roux, who faces a disciplinary hearing later Tuesday after appearing for Wales captain Alun Wyn Jones.
Irish coach Andy Farrell names his team on Wednesday with the French roster announced a day later.