He also urges Downing Street to put in place a substantial support program.
Changing from ‘medium’ to ‘high’ would bar Londoners from mingling with other households indoors, including in pubs and restaurants.
The Mayor of London asked for clarification on arrangements for businesses, support for vulnerable Londoners and testing and traceability efforts in the capital, including for those who are self-isolating after warning that the city is about to be.
The meeting was chaired by Secretary of Health Matt Hancock and Chief Medical Officer Chris Whitty, and an announcement could be made as early as Friday.
He also saw recommendations for much of the North West and North East and large parts of Yorkshire and the Midlands to be placed in “very high” level 3.
Boris Johnson is believed to be considering a version of a full two-week nationwide “circuit breaker” lockdown that scientists say could save thousands of lives – if his tiered system fails.
Labor leader Sir Keir Starmer broke ranks on Tuesday to demand new national restrictions to prevent the country from “sleepwalking into a long, dark winter” as infection rates soared.
The drastic measure could be scheduled to coincide with the English schools semester starting October 26.
A compromise, however, could see urban areas with a higher number of cases subject to temporary additional measures, reports the Times.
This would allow the Prime Minister to continue his regional approach and not be seen to bow down to Sir Keir.
Cabinet Minister Michael Gove and Senior Adviser Dominic Cummings are reportedly among those urging Mr Johnson to consider a full lockdown before the end of the month.
However, Chancellor Rishi Sunak has warned that even a minimal nationwide shutdown will push companies into bankruptcy and cause turmoil in the economy.
While science adviser Graham Medley has warned that it is too late for a breaker lockout to be fully effective.
In a letter to Mr Johnson, Mr Khan said that as the infection rate in London rapidly approached 100 cases per 100,000, it was “likely” that the capital would go to the alert level of level 2 starting this week.
“It is vital that London has the resources to engage, explain, encourage and enforce increased restrictions and uphold respect,” Khan said.
‘A London borough has done specific work to estimate the cost of providing this service for six months from November and it is £ 300,000 on top of the allocation that was recently allocated to councils to support the conformity.
“I am aware that these are discussions that have taken place with other regions that have had restrictions in place and the London government expects to have these discussions as well. ”
Mr Khan said the “unique circumstances” of the capital should be reflected in the approach and support.
He added: “The capital was particularly affected in the first wave, many of our communities and in particular the BAME community, suffering disproportionately.
“In addition, many families live in overcrowded housing and face high levels of homelessness and sleep the hard way.
“Our size and density present specific challenges, with the economic case for protecting businesses in the core business area overwhelming. ”
Among the demands, Khan called for clarity on what arrangements would be made available to businesses, warning that hundreds of thousands of jobs remain at risk in the capital.
He said it was “critical” for the government to resolve Transport for London’s (TfL) funding position, asking for a package for the network.
In addition to asking for clarification on support for vulnerable Londoners, the mayor called for an immediate increase in screening capacity, as well as a ‘redoubling’ of efforts to ensure screening of staff and residents.
“I will continue to urge Londoners to be vigilant, to follow the rules and to exercise caution,” he said in the letter.
“I accept that these new measures will have an impact on businesses and Londoners, but we have a joint responsibility to work together and do what we can to control this virus and save lives. ”
The mayor has previously insisted that London as a whole should adopt higher restrictions despite varying rates in the capital.
Mr Johnson, meanwhile, urged Sir Keir to persuade northern leaders to rally to the prospect of severe local restrictions during a heated debate in the House of Commons.
Greater Manchester Mayor Andy Burnham – a former Labor cabinet member under Gordon Brown – backed a national breaker on other local measures.
It comes after Northern Ireland enters a brief period of intense lockdown starting at 6 p.m. Friday, including shutting down schools for a fortnight and pubs and restaurants for a month after reporting 1,217 new cases on Wednesday.
The Welsh government, meanwhile, is set to introduce a ban on arrivals from areas of Britain with high infection rates after Prime Minister Mark Drakeford expressed disappointment that Downing Street did not have not imposed a border closure.
One hundred and thirty-seven more deaths and 19,724 new infections were reported in Britain on Wednesday.
And another 680 patients have been admitted to hospital with the virus, bringing the total for the past seven days to 4,576.