Louis Rees-Zammit and hooker Sam Parry are both set to make their international debuts on the bench. The game starts at 8:10 p.m. UK time.
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Wales: Leigh Halfpenny; George North, Jonathan Davies, Nick Tompkins, Josh Adams; Dan Biggar, Rhys Webb; Rhys Carre, Ryan Elias, Samson Lee, Cory Hill, Alun Wyn Jones (capitaine), Aaron Wainwright, Justin Tipuric, Taulupe Faletau.
Substitutes: Sam Parry, Nicky Smith, Dillon Lewis, Seb Davies, James Davies, Gareth Davies, Rhys Patchell, Louis Rees-Zammit.
France: Anthony Bouthier; Teddy Thomas, Vrimi Vakatawa, Gael Fickou, Vincent Rattez; Romain Ntamack, Antoine Dupont; Cyril Baille, Julien Marchand, Mohamed Haouas; Bernard Le Roux, Damien Willemse; François Cros, Charles Ollivon (capt), Gregory Aldritt.
Substitutes: Camille Chat, Jean-Baptiste Gros, Demba Bamba, Romain Taofifenua, Dylan Cretin, Baptiste Serin, Arthur Vincent, Thomas Ramos.
Kicks off at 8:10 p.m. UK time, live on S4C and ITV4
Live updates below: