Eddie fought a long battle with the disease for over ten years and was able to keep his disease a secret from fans as he continued to work and play.
Signs that the rocker was struggling were only revealed when he was unable to stick to his grueling schedule.
Eddie, who has been hailed as one of the best musicians of his generation, first spoke about his cancer in 2015 – years after his initial diagnosis.
He was first treated for tongue cancer in 2000, when surgeons were forced to remove a third of his tongue.
The operation was a success with Eddie declared cancer free in 2002, but sadly the disease returned a few years later.
Eddie remained optimistic, telling Billboard he had even quit smoking – after he got into the habit at the tender age of 12.
However, the guitarist had always been adamant that cigarettes had not been the cause of his ill health and instead believed that his habit of carrying a metal guitar pick in his mouth had caused cancer.
“I used metal picks – they’re brass and copper – that I always held in my mouth, exactly where I got the cancer of the tongue,” he said.
“Also, I mostly live in a recording studio filled with electromagnetic energy. So it’s a theory. I mean, I smoked and took a lot of drugs and a lot of everything. But at the same time, my lungs are totally clear. . It’s just my own theory, but the doctors say it’s possible.
In 2012, Eddie underwent emergency surgery after suffering from a severe episode of digestive upset diverticulitis.
The news was to be shared with the fans as Eddie was scheduled to take the stage in Japan.
A statement explaining the circumstances at the time read: “Eddie Van Halen underwent emergency surgery for a severe episode of diverticulitis. No further surgery is necessary and a full recovery is expected within 4-6 months. Van Halen’s planned visit to Japan in November 2012 is currently postponed and the band look forward to seeing and performing for their fans in 2013. ‘
Then in 2019, it was revealed that Eddie had been fighting throat cancer secretly for five years.
TMZ reported that the flip-flop was traveling back and forth to Germany for regular radiation to treat it.
It emerged when he was hospitalized after suffering severe abdominal pain when complications arose from the prescription drugs he took to treat the condition.
As soon as he was allowed to return home, Eddie began rehearsing music with his son Wolfgang, who joined Van Halen as bass player.
The ’80s rock group last performed together at the Hollywood Bowl in Los Angeles in October 2015.