The island of Montreal reported 411 new cases (34,823 in total), followed by Quebec with 153 (4,601 in total) and Montérégie with 142 new cases (11,124 in total).
In the last day, another person died of the illness, in addition to seven people who died between September 6 and October 1 and two people who died on an unknown date, officials said.
Four deaths have been reported in the Quebec City region, three in Chaudière-Appalaches, two in Montérégie and one in Laval.
There are now 77,380 positive COVID-19 cases in Quebec since the start of the pandemic, and 5,867 people have died.
After surging dramatically on Friday, the number of hospitalizations in the province increased by 24, and there are now 326 people receiving care in hospitals in Quebec. Of that number, 60 people are in the intensive care unit, an increase of 11.
Public health professionals analyzed 28,778 samples on October 1 (Quebec publishes two-day test data samples ahead of its daily updates).