Around 2.8 million people in Greater Manchester have joined some 3.1 million in Lancashire and the Liverpool City area already under the most severe restrictions in the early hours of Saturday.
In these areas, social mix is prohibited both indoors and in private gardens, while pubs and bars must close unless they can function as a restaurant.
The rule of six applies in some outdoor environments such as parks, public gardens, and sports fields.
Local leaders are helping the government determine whether other places should be closed, such as gyms or casinos.
In Greater Manchester, the new measures could lead to the closure of more than 1,800 pubs and 140 wine bars, as well as 277 betting houses and 12 casinos, according to real estate advisor Altus Group.
In the Liverpool city area, indoor gymnasiums and fitness studios were forced to close, as well as sports facilities, recreation centers, betting shops, adult gaming centers and casinos.
Gyms in Merseyside are now allowed to reopen in accordance with other areas subject to the more stringent local lockdown restrictions.
Gyms remain open in Lancashire, but the adult gaming industry, casinos, bingo halls, bookies and betting shops, and soft gaming areas have been closed.
Stores and places of worship can remain open, as can schools and colleges, while universities must reflect broader restrictions with the ability to upgrade to a more extensive online offering.
Up to 15 guests are allowed at weddings and 30 people can attend the funeral, with 15 people allowed at revivals, but wedding receptions are not allowed.
People living in level 3 zones are not recommended to stay overnight in other parts of the UK and should avoid traveling as much as possible in and out of the zone, unless it is for work, l education or family responsibilities.
Issue 10 confirmed that under Tier 2 and 3 rules on mixing households, people can still meet for business meetings indoors under certain circumstances.
What happens at level 2 and where is it affected?
Areas classified as high risk have restrictions on domestic mixing indoors while the rule of six continues to apply outdoors.
People should not socialize with their friends and family indoors in any place unless they live with them or have formed a supportive bubble with them.
Up to 15 guests are allowed at weddings and up to 30 people allowed at funerals, with 15 people allowed at receptions and awakenings.
Shops, gymnasiums, all educational establishments and places of worship may remain open, with overnight stays authorized.
The travel advice for those who live in level 2 areas is to reduce the number of trips they take where possible and avoid traveling to very high level 3 areas.
Les zones du niveau 2 comprennent Cheshire, Derbyshire, West Yorkshire, Durham, Northumberland, Tyne and Wear, Tees Valley, West Midlands et Leicestershire.
London, Essex, Elmbridge, Barrow-in-Furness, York, North East Derbyshire, Chesterfield and Erewash moved up to rank 2 last Saturday.
Wales Premier Mark Drakeford confirmed a two-week ‘firewall’ lockdown in the country from Friday to November 9, and people living under levels 2 and 3 in England were already banned from crossing the Welsh border from Friday last week.
What restrictions are imposed on level 1 zones?
Areas classified as medium risk, those in Tier 1, are subject to the same national measures that were common across England earlier this year.
These include the 10 p.m. curfew for pubs and restaurants and a ban on most gatherings of more than six people.
Up to 15 guests will be allowed at weddings and up to 30 people at funerals, including 15 at receptions and awakenings.
Shops, gymnasiums, all educational institutions and places of worship will remain open, with overnight stays allowed and no travel restrictions in the area, although people are advised to avoid traveling to areas of level 3 when possible.