A trial draft will include fines for drivers who break the new £ 100 lower limit and slap them with three points.
The measures will be deployed in four areas by the end of the month to assess the impact of the traffic slowdown on air quality, reports MailOnline.
Part of the M5 between junctions one and two is on the list. The stretch to Oldbury, West Bromwich, near Birmingham, is a busy place where the motorway meets the M6.
A separate part of the M6 in Birmingham, between junctions six and seven, as well as the M1 between junctions 33 and 34 in Rotherham and the M602 between junctions one and three near Eccles, Greater Manchester, are also shown on the list of targets.
The pilot, the first attempt to tackle emissions by lowering the 70 mph limit on highways, is expected to stay in place for 12 to 15 months.
Evidence shows that the reduced limit could lead to a 17% drop in air pollutants.
Highways England environmental manager Ivan Le Fevre told The Times: ‘Ultimately the air quality challenge will be solved’ at the tailpipe ‘by car manufacturers and the changes use of vehicles.
“Until that happens, we will continue our research and solutions program. “