Manchester remain on red alert with an infection rate now three times higher than the English average – which is 42.
The current infection rate in the city now stands at 153.2 per 100,000 residents in the seven days ending September 20.
Cases are also increasing rapidly in Bury.
The city now has the second highest infection rate in Greater Manchester – just behind Bolton where the rate is 212.8.
Bury recorded 173.3 cases per 100,000 population during the week ending September 20.
More than 300 people in the borough have tested positive for Covid-19 in just one week for the first time since the start of the pandemic.
Oldham, Rochdale, Salford, Tameside, and Wigan all still have infection rates above 100.
And the infection rate continues to rise in Stockport and Trafford, which currently have rates of 70.5 and 61.1 per 100,000 population during the week ending September 20, respectively.
Another person has died at Greater Manchester Hospital after testing positive for Covid-19 according to the latest figures released on Wednesday.
The death was registered with the Tameside & Glossop Integrated Care NHS Foundation Trust within the past 24 hours.
This brings the death toll in hospitals in the region to 2,250, according to the latest NHS figures.
Meanwhile, the UK today recorded its third highest number of coronavirus cases in 24 hours.
The latest figures show an additional 6,178 laboratory-confirmed coronavirus cases – the highest since May 1.
This is an increase of over 25% from yesterday’s 4,926 new positive cases.
Today’s total is only 23 fewer cases than the highest number of cases on record in a daily period in the UK, which saw 6201 people diagnosed with Covid-19 on the 1st may.
The most recent data shows that the total number of confirmed cases has now reached a total of 409,729.
It follows a sharp increase in the past few days with new cases reportedly doubling every seven days.
The government also said that at 9 a.m. on Wednesday, another 37 people had died within 28 days of testing positive for the disease.
This brings the total number of people who have died in the UK to 41,862.
Greater Manchester’s Andy Burnham was due to hold his weekly press conference today but it was postponed until Friday.
A statement by a spokesperson for the Greater Manchester Combined Authority said: ‘Following the Prime Minister’s address to the nation last night, the Mayor and leaders of Greater Manchester are digesting what it means for the nations and regions, in particular how national measures affect local restrictions currently in place. .
“Rather than adding to the confusion, we will comment on this after the National Government (Gold) decision-making meeting.
“Greater Manchester is in discussions with the government regarding its decision.”