It is said, she has cited irreconcilable differences.
The music mogul, 55, is married to the lawyer, 50, in 1996 and they have two adult children together.
The age of their children – son Truice, 23, and a girl Really, 19 – means that child support will not be a problem.
However, it is said that Nicole is asking for spousal support, and that they do not have to sign a pre-nuptial agreement before they tied the knot.
This means that Nicole could be entitled to half the rapper’s fortune.
What exactly is Dr Dre net?
The star is said to be worth the modest sum of $ 820 million, making him the fourth richest rapper in the world, behind Diddy ($885 million), Jay-Z ($1 billion) and Kanye West ($3.2 billion).
Eminem, Usher, and Drake also are in the top 10.
Part of Dre’s fortune comes from his founder of Beats Electronics brand.
He has sold his Beats by Dr. Dre brand to Apple several years ago for $ 3 billion.
The rapper is also the founder and ceo of Aftermath Entertainment, and was previously a co-owner of Death Row Records.
Nicole and Dr. Dre have made their last public appearance together in February, when they attended a Tom Ford fashion show with their daughter.
This month, he spoke of his wife as he discussed his upcoming birthday with BigBoyTV.
He said: “I have decided to keep it low-key this time — I’ll have a few friends and my wife is going to do a crab boil for me. I love the crab. We will just give a kick, kick in my garden. ”
Dr. Dre is a father of six, of five different women.
He was just 16 years old when he met with then-girlfriend Cassandra Joy Green and had their first child, a son named Curtis, who, he did not meet until 20 years later.
Dre’s son Andre Young Jr tragically passed away in 2008 at the age of 20 years. He had been at the centre of a broad contestation of paternity, with his mother, Jenita Porter, filed a lawsuit in search of $5,000 per month in child support.
Dr. is also the dad of son Marcel, who he shares with the singer Michel the.
He also has a daughter named Tanya.
Mirror Online has contacted Dr. Dre representatives for the comment.