Coronavirus vaccine “may never be found”


Elsewhere, Imperial Oil researchers have developed a candidate who, once injected, will provide genetic instructions to muscle cells to make the advanced surface protein of SARS-CoV-2.

This should provoke an immune response and create immunity against the virus.

The team, led by Professor Robin Shattock of the Imperial’s Infectious Diseases Department, has been testing the candidate on animals since early February.

Clinical trials are scheduled to start in June and the team will seek to recruit healthy adults to test the vaccine.

The results could be available as early as September, the researchers said. The trial is not yet open to recruitment, but will be announced in due course.

Dr. Katrina Pollock, clinical researcher in vaccinology, who will lead work on the Imperial Hammersmith campus, said, “This is the first human trial for this candidate vaccine and an important step towards the development of a safe and effective vaccine against the novel. coronavirus.

“Our clinical team is delighted to begin the trials as a key center in this historic study to combat Covid-19.”

UK Vaccine Task Force

On April 17, the government launched a task force designed to “rapidly develop a coronavirus vaccine”, as well as to expand manufacturing so that it can be quickly produced and delivered in large quantities.

It will be chaired by Sir Patrick Vallance and Professor Jonathan van Tam, the Deputy Chief Medical Officer of Health, and members will include AstraZeneca and the Wellcome Trust.

The government originally earmarked £ 14 million to invest in 21 coronavirus research projects – such as the work of scientists from the University of Oxford and Imperial College London. On April 21, an announcement of an additional £ 44.5 million for the Oxford and Imperial trials further increased this funding.

In America, the U.S. government has pledged to enter into a billion dollar (800 million pound) Covid-19 vaccine deal with titan Johnson & Johnson, co-funding research through Biomedical Advanced Research and Development Authority (Barda).

Human trials of the vaccine have already started in the United States, breaking records for the speed at which these trials can take off. Healthy volunteers in America are receiving the next generation “genetic hack” after bypassing standard animal testing in a very accelerated process.

US President Donald Trump has said he hopes a coronavirus vaccine will be available by the end of the year and has released details of the government’s campaign to help efforts dubbed “Operation Warp Speed” “

Trump said the United States would begin mass production of all developed vaccines before they are fully approved so that they can be quickly distributed once approved.

In addition to developing vaccines, doctors are testing existing drugs against viruses such as Ebola, malaria and HIV. Initial results look promising, but until the full clinical trials are completed, doctors cannot be sure that the drugs are working.

It has also been reported that GSK and Sanofi have joined forces to develop a treatment for coronaviruses and plan to prepare a vaccine for testing by the end of 2020.

How long does it take to make a vaccine and why?


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