According to the study, published in the journal Antiviral research, the drug, ivermectin, prevented the virus, SARS-CoV-2, from growing in cell culture within 48 hours.
“We found that even a single dose could essentially clear out all of the viral RNA in 48 hours and that even at 24 hours there was a really significant reduction,” said study co-author Kylie Wagstaff of l Monash University in Australia.
Scientists have said that ivermectin is an approved pest control drug that has also been shown to be effective in vitro against a wide range of viruses, including HIV, dengue, flu and Zika virus.
However, Wagstaff cautioned that the testing for the study was in vitro and that the testing should be done on people.
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“Ivermectin is widely used and considered to be a safe drug. We now need to determine whether the dosage you can use it in humans will be effective – this is the next step, “said Wagstaff.
“At a time when we are experiencing a global pandemic and there is no approved treatment, if we had a compound that was already available around the world, it could help people sooner,” she said. .
Although the mechanism by which ivermectin acts on the virus is not known, scientists have stated that it is likely, based on its action on other viruses, to work to prevent the virus from ” curb ”the ability of host cells to suppress it.
“As a virologist who was part of the team that was the first to isolate and share SARS-COV2 outside of China in January 2020, I am delighted with the prospect of ivermectin being used as potential COVID-19 drug, “said Leon Caly. , co-author of the Royal Melbourne Hospital study in Australia.
The scientists also warned that the use of ivermectin to fight COVID-19 would depend on the results of future preclinical tests and, ultimately, clinical trials.
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Update date: 06 Apr 2020 07:09:37 IST
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