Eddie, along with comedian Syd Little, was one of Britain’s most beloved comedy duos, known as Little And Large.
He died alone in hospital without family or friends being allowed to visit him due to strict rules about slowing the spread of the virus.
Her son Ryan McGinnis announced the sad news on Facebook, telling family and friends that his Scottish humorist father had died at the age of 78.
“It is with great sadness that Mom and I must announce that my father, Edward Mcginnis, died early in the morning,” he wrote.
“He suffered from heart failure and, unfortunately, at the hospital, he contracted the coronavirus, that his heart was unfortunately not strong enough to fight. “
“Dad has fought bravely for so long. Due to this horrible illness, we were unable to visit him at the hospital, but the whole family and close friends spoke to him every day.
“He will be sorely missed and we are so proud of all that he has accomplished in his career with Syd and we know that he was loved by the millions who watched them every week. “
“Daddy RIP. We love you and we miss you from the whole family. “
Eddie found fame alongside Syd in the talent show Opportunity Knocks, which they won in 1971.
He had suffered from poor health in recent years and had a heart transplant in 2003, which ended his double act and that of Syd.
He told the Mirror in 2017: “This phone call to Syd was the most painful I have ever had. I was crying because I knew I was putting him out of work. He had bills to pay.
“I felt horrible. We were not just a double act. We were friends from the start. “
Eddie leaves behind his second wife Patsy and three children, Samantha, Alison and Ryan