Brian Dennehy died at the age of 81 from natural causes.
His daughter Elizabeth confirmed on Twitter that the actor, who is best known for his roles in First blood and Tommy boy, died on Wednesday in Connecticut.
“It is with a heavy heart that we announce that our father, Brian, died last night of natural causes unrelated to Covid,” she writes.
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“Larger than life, generous at fault, proud and devoted father and grandfather, he will be sadly missed by his wife Jennifer, his family and many friends.”
Dennehy was widely respected for his work in film, television and theater, and is best known for playing the sheriff who pursues Sylvester Stallone’s John Rambo in the iconic action thriller of 1982.
In the beloved comedy of Chris Farley and David Spade Tommy boy, Dennehy played the role of Big Tom Callahan.
Throughout his career, he has also won a Golden Globe Award and five Primetime Emmys, as well as two Tony Awards for his acclaimed work on stage, in Death of a seller in 1999 and Long day trip at night in 2003.
Dennehy is survived by his wife and five children.